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A 438079 DEVD-FMK Lomeguatrib can be used with

SKU: 50936689881

4.3
EUR95.00 EUR126.00

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A 438079 DEVD-FMK Lomeguatrib can be used withA 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors

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Description

Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment

Smiles: C[C@H](CN1C=NC2=C(N)N=CN=C12)OCP(O)(O)=O

Ki = 37 nM

also known as NSC 74859

Formula: C17H15FN6O3

A 438079 DEVD-FMK Lomeguatrib can be used withA 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors

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