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International Consensus for Diagnosing Lipedema: Uncontrolled localized deposition of fat in the lower extremities Symmetric increase in adipose tissue (two-body syndrome) Onset at puberty, pregnancy, and menopause Women (usually progressive with age) Easy Bruising Tired or heavy legs Mild or severe pain or pressure to touch Hands and feet are usually spared Cuffing or bulging at the joints Stemmers sign is negative Nodules of fat are palpable Limited mobility and decreased social activity* *Adapted from Sandhofer M, et al

Prevalence of multiple chronic conditions among US adults: estimates from the National Health Interview Survey, 2010

Glucagon-like peptide analogs are superior for diabetes and weight control in patients on antipsychotic medications: a retrospective cohort study

Because individual responses vary, some people may notice irritability while others do not

Dietary modifications form the foundation of constipation management: Increase fiber intake : Aim for 25-30 grams daily through whole grains, fruits, vegetables, and legumes

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