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[37] Autoimmune disorders represent another important contraindication category for melatonin supplementation

10.1111/dom.14734 14 BonnetF.ScheenA

The sensations are real, can be uncomfortable, but dont involve muscle weakness or movement problems

A busy intensivist might see just a few cases during their career (unless theyre working in a transplant ICU)

The receptor-ratio tuning, the formulation and delivery layers, the method-of-use filings on indications that have not yet read out, and the combination claims that cross triples into amylin, calcitonin, and SGLT2 are the positions that will still be generating revenue in 2040