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Cambridge, MA (USA): Elsevier

After six weeks, the treated group lost small but significant amounts of body weight (1.4 kg) and body fat (2.9%)

Science 356 , eaal3321 (2017)

1-3 Actor portrayals IMCIVREE targets a root cause of hyperphagia and obesity in POMC, PCSK1, and LEPR deficiencies 1,2 Impaired MC4R pathway function 2 In people with POMC, PCSK1, or LEPR deficiency, genetic variants can cause disrupted signaling