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In this context, ultrasound survey of joints in subjects with asymptomatic hyperuricemia, discussed in Diagnosis of Gout and Use of Laboratory and Imaging , has noted evidence of articular surface urate crystal deposits in ~17% to 25% (of knees and toes) and intra-articular subclinical tophi in ~16%, with none in normouricemic controls

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32 Shor et al used a nationwide Canadian EHR database to compare 46,334 patients taking GLP-1 RAs with 92,668 controls over a follow-up period of 6 months to 3 years