Cdc25B(Phospho Ser353) Polyclonal Antibody, 20ul Molecular Sciences This gene is localized to

This gene is localized to 11q12| in a cluster of other family members

The protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation

Tissue specific transplantation antigen P35B is a NADP (H)-binding protein

and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain

Cdc25B(Phospho Ser353) Polyclonal Antibody, 20ul Molecular Sciences This gene is localized toCDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in