Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis NANOG plays a central role

NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells

This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development

The functions of human sirtuins have not yet been determined

Alternate splicing of this gene results in several transcript variants encoding different isoforms

and transcription factor erythroblastosis virus E26 oncogene homolog 1

Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis NANOG plays a central roleMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.