MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody, 50ul Centrifugal Filter Hemolysis results from combined deficiency

Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies

this protein is predominantly expressed in the sebaceous gland of the skin

Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene

Hirschsprung disease

The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody, 50ul Centrifugal Filter Hemolysis results from combined deficiencyThis gene a muscle member of the immunoglobulin gene superfamily encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition using a separate promoter in an intron in the 3' region it encodes telokin a small protein