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Liang Y, Liu J, Feng Z

This triple-receptor activity is one reason researchers are studying whether retatrutide may produce greater weight-loss effects than earlier incretin-based medications

By mimicking the hormone glucagon-like peptide-1, these medications reduce appetite, slow digestion, and improve insulin sensitivity

The ethanol extract at 200 and 400 mg/kg could strongly decrease IL-1, cartilage oligomeric matrix protein (COMP), hyaluronic acid (HA), malondialdehyde (MDA), and myeloperoxidase (MPO) serum levels compared to the control group not provided with the extract (Aborehab et al., 2017)

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