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Recently published retrospective cohort studies from the USA and Denmark using electronic health records and user surveys have reported that between 50 and 75 % of GBT users had stopped their treatment by one year [20,21,45,165]

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The combination of a GHRH analogue and a growth hormone secretagogue allows for investigation of parallel endocrine signaling pathways, receptor-mediated communication, intracellular signaling cascades, and broader neuroendocrine regulatory mechanisms

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Preclinical evidence supports potential efficacy across these substance classes, but human data remain sparse