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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels and large extracellular loops containing

SKU: 24381194506

4.7
PLN123.75 PLN153.75

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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels and large extracellular loops containingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and large extracellular loops containing multiple N-glycosylation sites

Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified

are membrane-bound proteins with long N termini containing multiple domains

SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif)

Ras homolog

Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels and large extracellular loops containingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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