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The two names most often discussed are Semaglutide (the active ingredient in Ozempic and Wegovy) and Tirzepatide (known by brand names Mounjaro and Zepbound)

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Where vomiting occurs over a prolonged period of months and years the more damage will occur

For example, in rats it reduces cardiac output, causes vasoconstriction and reduction in glomerular filtration rate, plasma renin and aldosterone activity