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NBEAL2 contains one BEACH domain and five WD repeats

Contains 1 IRS-type PTB domain

This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro| thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components

Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts

COL8A2 Polyclonal Antibody, 100ul Metabolic enzymes Take your research to theThis gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants.